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The use of displacement chromatography is quite constrained, and is generally useful for preparative chromatography. The basic principle relies on a molecule using a high affinity to the chromatography matrix (the displacer) which can be accustomed to compete correctly for binding web sites, and thus displace all molecules with lesser affinities.[2
Administration to Wistar rats for 2 yrs of two g/kg bw daily sodium saccharin during the drinking-h2o or of four g/kg bw daily while in the diet regime decreased the burden obtain markedly; fluid consumption was enhanced while in the latter team and lessened in the former. The typical urinary pH of males in the first group had risen to earlier ment
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